6Chapter 3. Organism-Niche Coupling and the Body's Energy Economy
42Chapter 39. Public Health Applications: Designing for Mitochondrial Life-Capacity
7Chapter 4. Mitochondrial Life-Capacity Defined
43Chapter 40. Civilizational Applications: Energy, Extraction, and the Life-Ground
8Chapter 5. Fatigue as the Felt Narrowing of Energy Affordance
44Chapter 41. The Life-Coherent Action Cycle for Mitochondrial Life-Capacity
9Chapter 6. Wu-Wei Physiology: Minimal Forcing as Biological Coherence
45Chapter 42. Clinical Ethics: From Blame to Life-Enabling Responsibility
10Chapter 7. The Electron Transport Chain as Flow Architecture
46Chapter 43. Why Measurement Must Serve Life-Capacity
11Chapter 8. Reductive and Oxidative Stress as Disturbed Flow
47Chapter 44. Measuring Mitochondrial Life-Capacity
12Chapter 9. Cristae Structure and the Architecture of Energetic Possibility
48Chapter 45. Dynamic Testing: Measuring Recovery, Not Only Resting State
13Chapter 10. Mitochondrial Dynamics: Fusion, Fission, Mitophagy, and Network Coherence
49Chapter 46. Measuring Fatigue as Energetic Affordance
14Chapter 11. Autophagy, Proteostasis, and the Cost of Maintenance
50Chapter 47. Measuring Restorative Margins
15Chapter 12. Mitochondrial Quality Control and Restorative Margins
51Chapter 48. Avoiding Metric Capture and Measurement Violence
16Chapter 13. The Energy Gap: When Demand Exceeds Transformation Capacity
52Chapter 49. Research Agenda I: Mechanisms of Energy-Gap Signaling
17Chapter 14. Local Compensation: Warburg-Like Metabolism and Redox Workarounds
53Chapter 50. Research Agenda II: Fatigue, Vitality, and Felt Capacity
18Chapter 15. Global Compensation: GDF15, FGF21, and Mitoceptive Escalation
54Chapter 51. Research Agenda III: Dynamic Recovery and Post-Exertional Physiology
19Chapter 16. Metaboception: The Brain's Model of the Body's Energy Budget
55Chapter 52. Research Agenda IV: Salugenesis, Repair, and Intervention
20Chapter 17. Fatigue as Energetic Affordance Perception
56Chapter 53. Research Agenda V: Salutogenic Affordances and Civilizational Burden
21Chapter 18. Anxiety, Valence, Arousal, and the Energetic Body Budget
57Chapter 54. Research Agenda VI: Equity, Margins, and Burden Distribution
22Chapter 19. Tired but Wired: Mobilization Without Resolution
58Chapter 55. Toward a Mitochondrial Life-Capacity Index
23Chapter 20. From Felt Capacity to Behavior: How the Body Conditions Human Doing
59Chapter 56. Methodological Principles for the Field
24Chapter 21. Vitality as Expanded Affordance
60Chapter 57. Evaluation Questions for Clinical Programs and Policies
25Chapter 22. Salugenesis as Mitochondrial Healing Completion
61Chapter 58. The Limits of the Framework
26Chapter 23. The Cell Danger Response and the Logic of Incomplete Healing
62Chapter 59. A Practical Research Roadmap
27Chapter 24. Autophagy, Mitophagy, and Proteostasis as Hidden Healing Labor
63Chapter 60. Conclusion of Part VI: Measurement as Accountability to Life
28Chapter 25. Sleep, Melatonin, and Circadian Repair
64Chapter 61. Discussion: From Mitochondrial Function to Life-Capacity
29Chapter 26. Movement, Pacing, and the Restoration of Flow
65Chapter 62. The Central Synthesis: Energy Flow, Repair, and Affordance
30Chapter 27. Nutrition, Substrate Quality, and Redox Burden
66Chapter 63. Fatigue Reconsidered: From Symptom to Signal
31Chapter 28. Belonging, Dignity, Meaning, and the Energetic Cost of Threat
67Chapter 64. Chronic Illness as Locked Compensation
32Chapter 29. The Salutogenic Affordance Field as Mitochondrial Infrastructure
68Chapter 65. The Life-Coherent Medical Imagination
33Chapter 30. Restorative Margins: The Space in Which Healing Becomes Possible
69Chapter 66. Implications for Public Health and Governance
34Chapter 31. From Repair to Participation: Healing Must Reopen Life
70Chapter 67. Limitations and Guardrails
35Chapter 32. From Mechanism to Practice: A Life-Coherent Clinical Method
71Chapter 68. Conclusion: Toward a Science of Mitochondrial Life-Capacity
36Chapter 33. Chronic Fatigue, ME/CFS, Long COVID, and Post-Infectious Syndromes