Health and Wellness

The Longevity Revolution

The Global Race to Unlock the Science of AgingBy Rio Vale

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Length13h 5m

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For centuries, aging was accepted as life’s only certainty. Now, a generation of scientists is betting it doesn’t have to be. Inside the world’s most advanced laboratories, researchers are dismantling the molecular machinery of aging piece by piece—silencing the genes that drive cellular decay, clearing the zombie cells that poison healthy tissue, and reprogramming the biological clock itself. The results are not the stuff of science fiction. They are published in peer-reviewed journals, funded by billions in venture capital, and moving—fast—toward human clinical trials. This is the story of that revolution in full: the Nobel laureates and startup founders, the geopolitical rivalries between the U.S., China, and Japan, and the staggering sums being wagered on the belief that aging is not destiny—it is a disease. And diseases can be treated.

Futuristic Genetic Engineering Exploration Artificial Intelligence Healing Survival Political Intrigue

Audiobook details

GenreHealth and Wellness

Length13 hrs 5 mins

Narrated byListen with 1,000+ voices

FormateBook with Audio

Publish dateMar 31, 2026

LanguageEnglish

1Dedication

2Acknowledgments

3Chapter 1: The Hallmarks: How Science Finally Found a Map of Aging

4Chapter 2: The Clock Inside: Epigenetics and the Measurement of Biological Age

5Chapter 3: Why We Age at All: The Evolutionary Logic of Senescence

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6Chapter 4: The Long-Lived: Lessons from Centenarians and Blue Zones

7Chapter 5: Worms, Flies, and Mice: The Model Organism Revolution

8Chapter 6: The Sirtuin Wars: NAD+, Resveratrol, and the Battle over Aging Science

9Chapter 7: Ghost Cells: The Rise of Senolytics

10Chapter 8: Rewriting the Code: Yamanaka Factors and the Reprogramming Revolution

11Chapter 9: The mTOR Maze: Rapamycin, Nutrient Sensing, and the Longevity Drug

12Chapter 10: The Telomere Question: Counting Down, Reaching Up

13Chapter 11: The Inflammation Engine: Inflammaging and the Body at War with Itself

14Chapter 12: Google Bets on Death: The Birth of Calico and the Age of Longevity Capital

15Chapter 13: The Billionaires’ Bet: Altos Labs and the Three-Billion-Dollar Gamble

16Chapter 14: The Longevity Startup Ecosystem: Senolytics, Biomarkers, and the New Aging Industry

17Chapter 15: The TAME Trial: The First FDA-Approved Study to Treat Aging as a Disease

18Chapter 16: The Reprogramming Companies: From Lab to Clinic

19Chapter 17: The Global Race: Asia, Europe, and the Geopolitics of Longevity Science

20Chapter 18: The Data Revolution: AI, Biobanks, and the Digital Hunt for Aging Drugs

21Chapter 19: The Access Question: Who Gets to Live Longer?

22Chapter 20: The Social Contract Under Pressure: Retirement, Pensions, and a World of Longer Lives

23Chapter 21: The Meaning of Mortality: Philosophy, Religion, and the Ethics of Extreme Longevity

24Chapter 22: The Regulatory Gauntlet: Can the FDA Keep Up with Aging Science?

25Chapter 23: The Skeptics: What the Longevity Optimists Get Wrong

26Chapter 24: The Self-Experimenters: Biohackers, Billionaires, and the Limits of Personal Science

27Chapter 25: The Horizon: What Victory Looks Like

28Character Guide

29References & Bibliography

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