Our Human Variability - A Conversation with Stephen Scherer
By Howard Burton
Length2h 50m
About this audiobook
This book is based on an in-depth conversation between Howard Burton and Stephen Scherer, the GlaxoSmithKline Research Chair in Genome Sciences at the Hospital for Sick Children and University of Toronto. Stephen Scherer discusses his lifelong passion for science that culminated in his groundbreaking discovery of copy-number variation. This conversation also covers his exciting work in autism research and how copy number variation brings us a deeper understanding of both human variability and disease.
This carefully-edited book includes an introduction, More Things in DNA, Horatio..., and questions for discussion at the end of each chapter:
I. James Watson’s Legacy - From The Double Helix to NRC to chromosome 7
II. In the Lab - The first hints of copy number variation
III. Chromosome 7 - Mapping genetic markers to chromosomes
IV. Back to Basics - Nucleotides, DNA, chromosomes, genes and mutations
V. Revolutionary Stirrings - Detecting copy number variation
VI. Going Global - Large-scale variation for all
VII. Variability and Evolution - Appreciating biological variability
VIII. Causes and Implications - Complexity galore: autism and other conditions
IX. Towards Treatment - Early diagnoses and equilibrium-restoring medicines
X. The Definition of Diseases - More complicated that you might think
XI. Probing Deeper - Stem cells, pleiotropy and environmental factors
XII. Ethical and Societal Issues - Towards responsible progress
XIII. Future Possibilities - Potentially unravelling biological complexity
XIV. Contact with Autism - Serendipitous occurrences
XV. Nobel Thoughts - The perks and perils of prizes
XVI. The Human Condition - Genetic windows on humanity
About Ideas Roadshow Conversations Series:
Presented in an accessible, conversational format, Ideas Roadshow books not only explore frontline academic research featuring world-leading researchers but also reveal the inspirations and personal journeys behind the research.
Audiobook details
GenreScience and Nature, Health and Wellness, Psychology
Length2 hrs 50 mins
Narrated byListen with 1,000+ voices
FormateBook with Audio
LanguageEnglish
Table of contents
1Introduction
20Questions for Discussion:
2A Note on the Text
21IX: Towards Treatment
3Introduction
22Questions for Discussion:
4The Conversation
23X. The Definition of Disease
5I. James Watson’s Legacy
24Questions for Discussion:
Show all chaptersShow less
6Questions for Discussion:
25XI. Probing Deeper
7II. In the Lab
26Questions for Discussion:
8Questions for Discussion:
27XII. Ethical and Societal Issues
9III. Chromosome 7
28Questions for Discussion:
10Questions for Discussion:
29XIII. Future Possibilities
11IV. Back to Basics
30Questions for Discussion:
12Questions for Discussion:
31XIV. Contact with Autism
13V. Revolutionary Stirrings
32Questions for Discussion:
14Questions for Discussion:
33XV. Nobel Thoughts
15VI. Going Global
34Questions for Discussion:
16Questions for Discussion:
35XVI. The Human Condition
17VII. Variability and Evolution
36Questions for Discussion:
18Questions for Discussion:
37Continuing the Conversation
19VIII. Causes and Implications
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