The Longevity Revolution

The Global Race to Unlock the Science of AgingBy Rio Vale
Listen with Sir Michael Caine™ and 1,000+ voices
Length13h 5m

About this audiobook

For centuries, aging was accepted as life’s only certainty. Now, a generation of scientists is betting it doesn’t have to be. Inside the world’s most advanced laboratories, researchers are dismantling the molecular machinery of aging piece by piece—silencing the genes that drive cellular decay, clearing the zombie cells that poison healthy tissue, and reprogramming the biological clock itself. The results are not the stuff of science fiction. They are published in peer-reviewed journals, funded by billions in venture capital, and moving—fast—toward human clinical trials. This is the story of that revolution in full: the Nobel laureates and startup founders, the geopolitical rivalries between the U.S., China, and Japan, and the staggering sums being wagered on the belief that aging is not destiny—it is a disease. And diseases can be treated.

Audiobook details

GenreHealth and Wellness
Length13 hrs 5 mins
Narrated byListen with 1,000+ voices
FormateBook with Audio
Publish dateMar 31, 2026
LanguageEnglish

Table of contents

1Dedication
2Acknowledgments
3Chapter 1: The Hallmarks: How Science Finally Found a Map of Aging
4Chapter 2: The Clock Inside: Epigenetics and the Measurement of Biological Age
5Chapter 3: Why We Age at All: The Evolutionary Logic of Senescence
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6Chapter 4: The Long-Lived: Lessons from Centenarians and Blue Zones
7Chapter 5: Worms, Flies, and Mice: The Model Organism Revolution
8Chapter 6: The Sirtuin Wars: NAD+, Resveratrol, and the Battle over Aging Science
9Chapter 7: Ghost Cells: The Rise of Senolytics
10Chapter 8: Rewriting the Code: Yamanaka Factors and the Reprogramming Revolution
11Chapter 9: The mTOR Maze: Rapamycin, Nutrient Sensing, and the Longevity Drug
12Chapter 10: The Telomere Question: Counting Down, Reaching Up
13Chapter 11: The Inflammation Engine: Inflammaging and the Body at War with Itself
14Chapter 12: Google Bets on Death: The Birth of Calico and the Age of Longevity Capital
15Chapter 13: The Billionaires’ Bet: Altos Labs and the Three-Billion-Dollar Gamble
16Chapter 14: The Longevity Startup Ecosystem: Senolytics, Biomarkers, and the New Aging Industry
17Chapter 15: The TAME Trial: The First FDA-Approved Study to Treat Aging as a Disease
18Chapter 16: The Reprogramming Companies: From Lab to Clinic
19Chapter 17: The Global Race: Asia, Europe, and the Geopolitics of Longevity Science
20Chapter 18: The Data Revolution: AI, Biobanks, and the Digital Hunt for Aging Drugs
21Chapter 19: The Access Question: Who Gets to Live Longer?
22Chapter 20: The Social Contract Under Pressure: Retirement, Pensions, and a World of Longer Lives
23Chapter 21: The Meaning of Mortality: Philosophy, Religion, and the Ethics of Extreme Longevity
24Chapter 22: The Regulatory Gauntlet: Can the FDA Keep Up with Aging Science?
25Chapter 23: The Skeptics: What the Longevity Optimists Get Wrong
26Chapter 24: The Self-Experimenters: Biohackers, Billionaires, and the Limits of Personal Science
27Chapter 25: The Horizon: What Victory Looks Like
28Character Guide
29References & Bibliography
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